Shigeki Nabeshima Selected Research

15- methyl- 8- aza- 16- oxagona- 1,3,5(10),13- tetraen- 17- one (MAOTO)

7/2022	Maoto, a traditional herbal medicine, for post-exposure prophylaxis for Japanese healthcare workers exposed to COVID-19: A single center study.
1/2021	Effects of maoto (ma-huang-tang) on host lipid mediator and transcriptome signature in influenza virus infection.
1/2017	Deconstructing the traditional Japanese medicine "Kampo": compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms.
1/2017	Maoto, a Traditional Japanese Herbal Medicine, Inhibits Uncoating of Influenza Virus.
8/2012	A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza.

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Shigeki Nabeshima Research Topics

Disease

6	Infections 07/2022 - 08/2002
5	Human Influenza (Influenza) 09/2021 - 03/2007
3	Fever (Fevers) 09/2021 - 08/2012
3	Chronic Hepatitis C 04/2006 - 06/2002
2	COVID-19 07/2022 - 05/2022
2	Chronic Renal Insufficiency 12/2021 - 07/2021
2	Hepatocellular Carcinoma (Hepatoma) 04/2006 - 02/2006
2	HIV Infections (HIV Infection) 01/2006 - 12/2002
2	Tuberculosis (Tuberculoses) 10/2005 - 02/2005
2	Viremia 07/2005 - 03/2002
1	Cross Infection (Nosocomial Infection) 07/2022
1	Chest Pain (Chest Pains) 01/2022
1	Respiratory Syncytial Virus Infections 01/2022
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022
1	Hypertension (High Blood Pressure) 12/2021
1	Atherosclerosis 07/2021
1	Weight Gain 07/2021
1	Obesity 07/2021
1	Endocarditis 06/2021
1	Heart Murmurs (Heart Murmur) 06/2021
1	Inflammation (Inflammations) 01/2017
1	Body Weight (Weight, Body) 01/2017
1	Cerebral Toxoplasmosis 02/2007
1	Facial Paralysis (Facial Palsy) 01/2006
1	Deglutition Disorders (Dysphagia) 01/2006
1	Hoarseness 01/2006
1	Polyneuropathies (Polyneuropathy) 01/2006
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 07/2005
1	Hypopituitarism (Sheehan's Syndrome) 07/2005
1	Parkinsonian Disorders (Parkinsonism) 07/2005
1	Disseminated Intravascular Coagulation 07/2003
1	Neoplasms (Cancer) 07/2003
1	Lymphadenopathy 12/2002
1	Leukocytosis (Pleocytosis) 09/2002
1	Bone Resorption 08/2002
1	Edema (Dropsy) 08/2002

Drug/Important Bio-Agent (IBA)

5	15- methyl- 8- aza- 16- oxagona- 1,3,5(10),13- tetraen- 17- one (MAOTO)IBA 07/2022 - 08/2012
3	Interferon-alpha (Interferon Alfa)IBA 04/2006 - 07/2005
3	RNA (Ribonucleic Acid)IBA 07/2005 - 03/2002
2	AntigensIBA 09/2021 - 10/2005
2	Pharmaceutical PreparationsIBA 01/2017 - 07/2004
2	CytokinesIBA 07/2005 - 06/2002
2	InterferonsIBA 07/2005 - 03/2002
1	BNT162 VaccineIBA 05/2022
1	COVID-19 VaccinesIBA 05/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	TroponinIBA 01/2022
1	Uric Acid (Urate)IBA 12/2021
1	OF 900IBA 09/2021
1	LDL Lipoproteins (beta Lipoproteins)IBA 07/2021
1	LDL CholesterolIBA 07/2021
1	oxidized low density lipoproteinIBA 07/2021
1	CoagulaseIBA 06/2021
1	Mao-toIBA 01/2021
1	LipidsIBA 01/2021
1	Toll-Like Receptor 3IBA 01/2017
1	Neuraminidase (Sialidase)IBA 08/2012
1	Zanamivir (Relenza)FDA Link 08/2012
1	Oseltamivir (Tamiflu)FDA Link 08/2012
1	Hepatitis B Vaccines (Hepatitis B Vaccine)IBA 03/2007
1	Interleukin-15 (Interleukin 15)IBA 04/2006
1	Acyclovir (Aciclovir)FDA LinkGeneric 01/2006
1	GlycolipidsIBA 10/2005
1	Hydrocortisone (Cortisol)FDA LinkGeneric 07/2005
1	Ribavirin (Virazole)FDA LinkGeneric 07/2005
1	SodiumIBA 07/2005
1	VaccinesIBA 02/2005
1	Tuberculin (PPD)IBA 02/2005
1	Chemokine ReceptorsIBA 07/2004
1	Dacarbazine (DIC)FDA LinkGeneric 07/2003
1	Fluorouracil (Carac)FDA LinkGeneric 07/2003
1	Leucovorin (Folinic Acid)FDA Link 07/2003
1	Blood Coagulation Factors (Coagulation Factor)IBA 07/2003
1	Alkaline PhosphataseIBA 07/2003
1	EnzymesIBA 12/2002
1	AntibodiesIBA 12/2002
1	ImmunosorbentsIBA 12/2002
1	C-Reactive ProteinIBA 09/2002
1	Ferritins (Ferritin)IBA 09/2002
1	Immunoglobulin A (IgA)IBA 08/2002
1	Antinuclear AntibodiesIBA 08/2002
1	DNA ProbesIBA 03/2002

Therapy/Procedure

5	Therapeutics 01/2022 - 07/2003
3	Highly Active Antiretroviral Therapy (HAART) 01/2006 - 12/2002
2	Oral Administration 07/2022 - 01/2021
2	Kampo Medicine (Kampo) 01/2021 - 01/2017